Continued. As odd as it may seem, pain medicines like opioids are not very effective. Over-the-counter NSAID pain medications like ibuprofen or aspirin don’t work well by themselves, but they. Fibromyalgia is characterised by persistent, widespread pain and tenderness, sleep problems, and fatigue. Common pain-relieving medicines such as paracetamol and ibuprofen are not usually considered effective. Fibromyalgia is a long-lasting or chronic disorder that causes muscle pain and fatigue (feeling tired). The symptoms of fibromyalgia are pain and tenderness throughout your body. Amplified fibromyalgia pain is often described as a deep or dull ache that starts in the muscles and radiates to other parts of the body. Some people also have a pins and needles sensation. Body aches and pains can be disruptive and frustrating. Learn many chronic pain causes, including lupus, arthritis, fibromyalgia, chronic fatigue, influenza, and vitamin deficiency. Find treatments that can ease whole body pain and bring relief, such as meditation and self-management. User Reviews for Hydrocodone / ibuprofen. Also known as: Ibudone, Reprexain, Xylon 10, Vicoprofen. The following information is NOT intended to endorse drugs or recommend therapy. Does anyone know how to wean off of meloxicam or can you just stop taking it like Ibuprofen & take? Asked 10 Jul 2012 by reelwater Updated 26 July 2018 Ibuprofen is known to interact with many different drugs. It's always important to share with your doctor and pharmacist all prescription, non-prescription, illegal, recreational, herbal. Newly Diagnosed Patients. Robert Bennett, MD. Fibromyalgia (fi-bro-my-AL-ja) is a very common condition of widespread muscular pain and fatigue. Seven to ten million Americans suffer from fibromyalgia (FM). Ibuprofen is an medicine used to manage mild to moderate pain, fever, inflammation, menstrual cramps, and types of arthritis. Common side effects are drowsiness, nausea, diarrhea, constipation, and ringing in the ears. Ibuprofen is an NSAID, which can cause stomach ulcers in some people. It also interacts with many other drugs.